研發人才




華國媛

分子科學與工程系

學經歷:
  學歷
美國約翰霍普金斯大學 生物化學,細胞,及分子生物學博士(1990/09-1997/02)
美國威斯康辛大學 微生物及遺傳學 雙主修(1986/09-1990/09)

經歷
國立臺北科技大學分子科學系及高分所專任副教授(2010/07~)
國立臺北科技大學分子科學系及高分所專任助理教授(2004/08-2010/07)
國立臺北科技大學生醫產業中心-執行長/主任(2005-2009)
國立臺北科技大學安環中心-主任(2007-2009)
台北醫學大學兼任助理教授(2001-2009)

國科會原住民健康藍圖計畫--總主持人(2007-2009)
行政院衛生署原住民健康諮詢委員(2009)
台灣Biobank先期計畫倫理委員會委員(2009)
台灣原住民醫學會常務理事(2009)
經濟部中小企業關懷計畫專家(2009)
教育部原住民教育白皮書委員(2009)

美國S&P 500 Vista專家(2006-2009)
BSBT 2009, Jeju, Korea, December 10 - 12,Section chairman(2009)
ICUT-2009, Fukuoka, Japan, Dec 20-22, Program committee member(2009)
Journal of Internet Technology, reviewer(2009)

美國ASBMB-科學競賽國際裁判(2007、2008)
PEPCON 2008- section chairman(2008)
BSBT 2008- section chairman(2008)
行政院衛生署國民健康局- 「2020健康白皮書」核心委員(2008)
IEEE FBIT 2007- section chairman(2007)
中研院國內學者(2005)
基因數碼科技股份有限公司:董事/研發副總(2002)
國泰醫學中心汐止研究中心:研究員/主任(2000)
中央研究院:博士後研究學者(1997)

專業技術
  基因體、蛋白質體、醣質科學、生物資訊管理、生物科技商務管理、醫療政策
   
研發介紹
  ◎ 期刊論文
  KY Hwa*, WM Lin, YI Hou, and T.M. Yeh* (2008), Peptide Mimicryingn between SARS Coronavirus Spike Protein and Human Proteins reacts with SARS Patient serum, J of Biomed and Biotech, accepted in press (SCI- 1.829, NSC92-2751-B006-Y).

KY Hwa*, TL Pang , MY Chen* (2007), Classification of LARGE-liked GlcNAc-transferases of Dictyostelium discoideum by Phylogenetic Analysis, IEEE CS Proceedings, FBIT2007, 386-391 (EI citation).

KY Hwa*, W M Lin, YI Ho, TM Yeh* (2007) Molecular Mimicry between SARS Coronavirus Spike Protein and Human Protein (2007), IEEE CS Proceedings, FBIT2007, 400-405 (EI citation, NSC92-2751-B006-Y).

KY Hwa*, HH Hung, CH Chen, (2007), Phylogenetic Analysisof Trichomonade Xylosyltransferases, IEEE CS Proceedings, FBIT2007, 406-411 (EI citation).

YS Lin, CF Lin, YT Fang, YM Kuo, PC Liao, TM Yeh TM, KY Hwa, CC Shieh, JH Yen, HJ Wang, IJ Su, HY Lei, (2005), Antibody to severe acute respiratory syndrome (SARS)-associated coronavirus spike protein domain 2 cross-reacts with lung epithelial cells and causes cytotoxicityl. Clin Exp Immunol 141(3):500-8 (SCI- 2.747, NSC92-2751-B006-Y )

KY Hwa*, New Drug Discovery through IT-Technology, 2005, UN-APCTT meeting, Academia collection, 1, 223-232.

SM Wu, WC Kuo, WL Hwu, KY Hwa, and YM Lee, (2004), RNF4 is a coactivator for NF-Y on GTP cyclohydrolase I proximal promoter. Molecular Pharmacology (SCI- 4.469, NSC93-2311-B-001-074-).

WL Hwu, MY Leu, KY Hwa, SW Fan, YM Lee, (2004), Molecular chaperones affect GTP cyclohydrolase I mutations in dopa-responsive dystonia. Ann Neurolog, 55(6): 875-8. (SCI- 8.051, NSC)
  ◎ 研討會論文
  KuoYuan Hwa*, Knowledge Management on the Novel LAGE-liked GlcNAc-transferase Protein Family, BSBT 2008, Hainan Island, China

KuoYuan Hwa*, Elucidating Antibacterial Mechanism of a Drug Candidate by Proteomics Approach, BSBT 2008, Hainan Island, China

KuoYuan Hwa*, et al, Addressing Health Disparities in Indigenous Taiwanese Communities, PRIDCO 2008, Kaua'I Island, USA

KuoYuan Hwa*, Discovery of Uniquenesses in Protein Glycosylation of Protozoa via Bioinformatics Tools, PepCon 2008, Shenzhen, China

KuoYuan Hwa*, Overexpression of YTCa, a novel gene can promote growth of NIH3T3 cells, EB 2008, San Diego, USA

ZY Liu and KY Hwa*, 2008, Preparation of tosylated mannan and tosylated pectin, which can inhibit the u937 cell growth, 台日分子科學國際會議, Taipei, Taiwan

ZY Liu, KY Hwa*, 2008, Preparation of chemically modified polysaccharide, 台灣生醫年會2008, Taipei, Taiwan

ZY Liu, KY Hwa*, 2007, Preparation of chemically modified tosylated mannan, 中國化學年會2007, Tainan, Taiwan

KY Hwa, 2007, Novelties in N-linked glycans of ancient protozoan parasites, MICC-3, Taipei, Taiwan

KY Hwa*, DS Chiang, CW Yao, 2007, Elucidating antibacterial drug action by proteomics approach, ASBMB meeting 2007, Washington D. C., USA.

KY Hwa*; HS Hung; KH Khoo, 2006, Functional and structural analysis of N-linekd Glycans of Trichomonas vaginalis, the 2006 Glycobiology Conference, Los Angles, USA.

HH Hung and KY Hwa*, 2006, Phylogenetic Tree based on protein –coding genes of xylosyltransferases is similar to the universal tree of life based on rRNA sequences, 2006第十一屆生物物理新知研討會, Taipei, Taiwan

KP Wang and KY Hwa*, 2006, Sequence Alignment of LPG1 from Leishmania Isolates of Different Pathogenic Group, 台日分子科學國際會議, Taipei, Taiwan

CS Liao and KY Hwa*,2006, Expression of perlecan andα-dystroglycan in human serum of cirrhosis and healthy individuals, 台日分子科學國際會議, Taipei, Taiwan

ST Chen and KY Hwa*, 2006, Construct the web-based antibiotic 2-D PAGE database, 台日分子科學國際會議, Taipei, Taiwan

KY Hwa*, KP Chang, KK Khoo, 2006, Correlation pathological spectra of leishmaniasis and parasitic glycoconjugates, ASBMB meeting 2006, San Francisco, USA

HH Hung and KY Hwa*, 2005, In silico identification of trichomonade xylosyltransferase via genomewide scanning” 台灣水產學2005年會, Ping Tong, Taiwan

SC Chen and KY Hwa*, 2005, Biological evaluation of polysaccharide-conjugated BSA, 台灣水產學會2005年會, Ping-Tong, Taiwan

SC Chen and KY Hwa*, 2005, Preparation and Application of Polysaccharides conjugated bovine serum albumin, 中國化學2005年會, Tainan, Taiwan

CS Liao and KY Hwa*, 2005, Expression of α-dystroglycan in human serum of cirrhosis and healthy individuals, 中國化學2005年會Tinan, Taiwan

M KS Lee and KY Hwa, 2004, Application of the circular form trypanosome artificial mini-chromosome plasmids for gene expression in Trypanosoma brucei, Molecular Parasitology Meeting, Woods Hole, USA
  ◎ 國科會計畫
  原住民國民中小學健康醫學教育課程教學與評量模式--原住民國中小健康醫學教育:原住民國中小學「醫療科學與人文」教育課程之設計(2009/09/01-2010/07/31, 1/4)

建構了解原住民族健康議題的藍圖-建構了解原住民族健康議題的藍圖(96/12/01-98/11/30)

建構了解原住民族健康議題的藍圖-探討台灣原住民肺結核病患者遵醫囑行為之心理與社會因素(96/12/01-98/11/30)

真核細胞之新型GlcNAc轉移?的功能研究與生醫診斷應用(97/08/01-98/07/31)
   
專利介紹
 
  喹林衍生物及其應用  
Provided is a quinoline derivative of Chemical For......
 
  新型之抗癌藥物篩選平台及其產物  
一種式(I)喹啉衍生物,其中,R1為視需要經取代之苯基;R2為鹵素;以及R3為視需要經取代之苯基,且......