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新型之抗癌藥物篩選平台及其產物 


專利名稱 喹林衍生物及其應用
專利國家
   專利證書號
美國 US8,552,029B2
專利權人 國立台北科技大學
發明人 華國媛、李玉梅、陳義龍、曾誠齊、卓心媛
應用領域
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技術摘要


Provided is a quinoline derivative of Chemical Formula

Figure US08552029-20131008-C00001
wherein, R1 is a substituted or unsubstituted phenyl group, R2 is a halogen, and R3 is a substituted or unsubstituted phenyl group, and one of the carbon atoms in the phenyl ring of the phenyl group is optionally substituted by a nitrogen atom (N). The quinoline derivative can efficiently inhibit cancer cell proliferation and can be used for treating cancer, especially for treating cancers related to the Janus kinase-signal transducers and activators of transcription (JAK-STAT) pathway and/or the mitogen-activated protein kinase (MAPK) pathway.


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